Manchester United vs Chelsea: Predictions, Odds, Lineups, Preview

• Coral predicts a 2-1 win for Manchester United in their home match at Old Trafford against Chelsea on Saturday afternoon.

• Man United's only win of the season came against Burnley, but Coral is tipping them to take their points tally to seven come the end of the weekend.

• Chelsea have a tricky Champions League fixture against Bayern Munich in the week, while Man United head into the game off the back of a six-day break.

Explore Coral’s detailed preview for Manchester United vs Chelsea in the Premier League. Stats, odds, predictions, and lineups for the 17:30 BST match.

• Fixture: Manchester United vs Chelsea

• Date: Saturday, 20 September 2025

• Kick-off: 17:30 BST

• Venue: Old Trafford

Match Prediction: Manchester United 2-1 Chelsea

Manchester United's recent form has been inconsistent, with a heavy defeat to Manchester City and a narrow loss to Arsenal, but they showed resilience in their win against Burnley.

They might look to exploit Chelsea's occasional defensive lapses, as seen in their draw against Brentford, by using the pace and creativity of players like Amad Diallo and Bryan Mbeumo. United's midfield, led by Bruno Fernandes, will need to control the game's tempo to counter Chelsea's attacking threats.

Chelsea, on the other hand, has been more consistent, with strong wins against Fulham and West Ham. Their attacking prowess, demonstrated by their 5-1 thrashing of West Ham, could pose significant problems for Manchester United's defence.

However, their inability to break down Crystal Palace at home suggests they might struggle if United sit deep and counter-attack effectively.

Manchester United's recent form has been a mix of highs and lows, with a convincing win against Burnley sandwiched between losses to Manchester City and Arsenal. 

Their ability to score against Burnley shows they can be dangerous going forward, but their defensive frailties, as seen in the heavy defeat to Manchester City, could be a concern.

This inconsistency might lead them to adopt a more cautious approach against Chelsea, focusing on counter-attacks and exploiting spaces left by Chelsea's attacking play.

Recent Premier League Results:

• Loss: 0-3 vs Manchester City (A)

• Win: 3-2 vs Burnley (H)

• Draw: 1-1 vs Fulham (A)

• Loss: 0-1 vs Arsenal (H)

Chelsea have shown good form recently, with two wins and two draws in their last four league games. Their attacking display against West Ham and solid victory over Fulham indicate they can dominate games when in form. 

However, their draws against Brentford and Crystal Palace suggest they can be vulnerable, particularly away from home.

This might encourage them to take the initiative early in the game against Manchester United, aiming to control possession and create scoring opportunities.

Recent Premier League Results:

• Draw: 2-2 vs Brentford (A)

• Win: 2-0 vs Fulham (H)

• Win: 5-1 vs West Ham United (A)

• Draw: 0-0 vs Crystal Palace (H)

Historically, the head-to-head record between Manchester United and Chelsea has been closely contested, with each team securing victories and draws in recent encounters. Chelsea has won two of the last five meetings, while Manchester United has won two, with one draw, indicating that neither team has a clear upper hand.

Recent Premier League Results

• Chelsea 1-0 Manchester United (16 May 2025)

• Manchester United 1-1 Chelsea (03 Nov 2024)

• Chelsea 4-3 Manchester United (04 Apr 2024)

• Manchester United 2-1 Chelsea (06 Dec 2023)

• Manchester United 4-1 Chelsea (25 May 2023)

• Lisandro Martínez (Knee) - Out

• Mason Mount (Knock) - Out

• Matheus Cunha (Hamstring) - Out

• Diego Dalot (Muscle) - Out

• Dário Essugo (Thigh) - Out

• Liam Delap (Hamstring) - Out

• Levi Colwill (Knee) - Out

• Mykhailo Mudryk (Suspended) - Out

• Benoît Badiashile (Fitness) - Doubt

• Bayındır, Yoro, De Ligt, Shaw, Mazraoui, Fernandes, Ugarte, Dorgu, Mbeumo, Diallo, Sesko

Manchester United's predicted lineup suggests a focus on attacking transitions, with players like Amad Diallo and Bryan Mbeumo likely to be key in exploiting spaces. The inclusion of Bruno Fernandes in a more defensive role indicates a strategy to control the midfield and launch quick counter-attacks.

• Sánchez, James, Adarabioyo, Chalobah, Cucarella, Fernández, Caicedo, Neto, Palmer, Gittens, Pedro

Chelsea's predicted lineup points towards a balanced approach, with Enzo Fernández and Moisés Caicedo anchoring the midfield to control the game's tempo. The presence of João Pedro and Cole Palmer suggests they will look to exploit any defensive lapses from Manchester United with quick, incisive attacks.

• Bruno Fernandes vs Enzo Fernández: This midfield battle will be crucial in determining which team can control the game's tempo.

• Luke Shaw vs Pedro Neto: Shaw's defensive skills will be tested against Neto's attacking prowess.

• Altay Bayındır (Manchester United): The goalkeeper's performance will be vital in keeping Chelsea's potent attack at bay.

• João Pedro (Chelsea): His ability to score and create chances could be the difference in a tight game.

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Odds and market details are accurate as of the time of publication.