Benfica vs Bayer Leverkusen: Predictions, Betting odds, Lineups, Preview

Explore Coral's detailed preview for Benfica vs Bayer Leverkusen in the UEFA Champions League. Stats, odds, predictions, and lineups for the 20:00 GMT match.

• Fixture: Benfica vs Bayer Leverkusen

• Date: Wednesday, 05 November 2025

• Kick-off: 20:00 GMT

• Venue: Estádio do Sport Lisboa e Benfica

Benfica's recent form has been inconsistent, with three losses in their last five matches. They have struggled to score, managing only one goal in their last three games. However, playing at home against Fenerbahce, they secured a win and a draw, suggesting they can be competitive when playing in front of their fans. This match against Bayer Leverkusen could see Benfica looking to exploit their home advantage and regain some confidence.

Bayer Leverkusen, on the other hand, have had mixed results recently, with a heavy defeat to Paris Saint Germain at home but managing draws against PSV Eindhoven and FC Copenhagen. Their attacking play has been inconsistent, but they have shown resilience in their away games. This could be a closely contested match, with Leverkusen's ability to score goals potentially making the difference. Both teams will be eager to secure a win to boost their campaign.

Benfica's recent form has been poor, with three losses in their last five matches, including heavy defeats against Newcastle and Chelsea. Their only win came at home against Fenerbahce, suggesting they perform better in front of their home crowd. This inconsistency could affect their confidence going into the match against Bayer Leverkusen, but playing at home might give them the boost they need to perform better.

• Loss: 0-3 vs Newcastle (A)
• Loss: 0-1 vs Chelsea (A)
• Loss: 2-3 vs Qarabag (H)
• Win: 1-0 vs Fenerbahce (H)
• Draw: 0-0 vs Fenerbahce (A)

Bayer Leverkusen have had a challenging run recently, with a significant loss to Paris Saint Germain at home. However, they managed to secure draws against PSV Eindhoven and FC Copenhagen, showing some resilience. Their ability to score goals has been inconsistent, but their recent performances suggest they can compete against strong teams. This could give them the edge in their upcoming match against Benfica.

• Loss: 2-7 vs Paris Saint Germain (H)
• Draw: 1-1 vs PSV Eindhoven (H)
• Draw: 2-2 vs FC Copenhagen (A)

The head-to-head record between Benfica and Bayer Leverkusen shows two previous encounters. In their most recent meeting in December 2014, the match ended in a 0-0 draw. Prior to that, in October 2014, Bayer Leverkusen secured a 3-1 victory over Benfica. This suggests that Bayer Leverkusen have had the upper hand in their past meetings, but the most recent result indicates a closely contested match could be on the cards.

• Benfica 0-0 Bayer Leverkusen (09 Dec 2014)
• Bayer Leverkusen 3-1 Benfica (01 Oct 2014)

• A. Bah (Knee Injury) - Out

• Bruma (Achilles Tendon Injury) - Out

• G. Prestianni (Inactive) - Out

• Manu (Knee Injury) - Out

• E. Palacios (Groin Injury) - Out

• M. Tillman (Muscle Injury) - Out

• N. Tella (Knee Injury) - Out

• A. Tape (Hamstring Injury) - Doubt

• Lucas (Muscle Injury) - Doubt

• Predicted lineup: Trubin (GK), Dedic (DF), Silva (DF), Otamendi (DF), Araujo (DF), Aursnes (DF), Lukebakio (MF), Rios (MF), Barrenechea (MF), Sudakov (MF), Pavlidis (AT)

Benfica's predicted lineup suggests a focus on defensive stability with Otamendi and Silva at the back, while relying on Pavlidis to lead the attack and create scoring opportunities.

• Predicted lineup: Flekken (GK), Bade (DF), Tapsoba (DF), Andrich (MF), Arthur (MF), Fernandez (MF), Garcia (MF), Grimaldo (MF), Echeverri (MF), Poku (AT), Kofane (AT)

Bayer Leverkusen's predicted lineup indicates a balanced approach, with Fernandez and Grimaldo in midfield to control the game's tempo, and Poku and Kofane up front to exploit any defensive weaknesses.

• Pavlidis vs Bade: This will be a crucial battle between Benfica's striker Pavlidis and Bayer Leverkusen's defender Bade, with Pavlidis looking to break through Bade's defensive line.
• Lukebakio vs Grimaldo: The duel between Benfica's midfielder Lukebakio and Bayer Leverkusen's midfielder Grimaldo will be key, as both players will aim to control the midfield and influence the game's flow.
• Barrenechea (Benfica): Barrenechea's role in Benfica's midfield will be vital, as he looks to provide stability and support both defensively and in transitioning to attack.
• Fernandez (Bayer Leverkusen): Fernandez's presence in Bayer Leverkusen's midfield will be crucial, as he aims to dictate the pace of the game and create scoring opportunities for his team.

Fans in the UK are able to watch Benfica vs Bayer Leverkusen on TNT Sports 6 at 20:00 GMT on Wednesday, 05 November 2025

Coral is predicting that the score will be 1-2 in the match between Benfica and Bayer Leverkusen

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