Sheffield United vs Southampton: Predictions, Betting odds, Lineups, Preview

Explore Coral's detailed preview for Sheffield United vs Southampton in the Championship. Stats, odds, predictions, and lineups for the 19:45 BST match.

• Fixture: Sheffield United vs Southampton

• Date: Tuesday, 30 September 2025

• Kick-off: 19:45 BST

• Venue: Bramall Lane

Match Prediction: Sheffield United 1-0 Southampton

Sheffield United, despite a recent string of losses, showed resilience in their 1-0 victory against Oxford United away from home. This suggests they might be able to capitalise on home advantage against Southampton, who have struggled to secure wins recently, drawing three of their last five matches. Sheffield's playing style could focus on a solid defensive setup, aiming to counter-attack effectively, which might exploit Southampton's inconsistent form.

Southampton, on the other hand, have been unable to convert draws into wins, which could indicate a lack of cutting edge in front of goal. Their recent 1-3 loss to Hull City away from home highlights potential vulnerabilities in their defence that Sheffield United might target. The game could be closely contested, with Southampton needing to find a way to break down Sheffield's defence while maintaining their own backline.

Sheffield United's recent form has been poor, with four losses in their last five games, including heavy defeats like the 0-5 loss to Ipswich Town. However, their 1-0 win against Oxford United away from home shows they can still produce a result when needed. This mixed form might lead to a cautious approach in this match, focusing on a strong defensive performance to secure a much-needed home win.

• Win: 1-0 vs Oxford United (A)

• Loss: 0-1 vs Charlton Athletic (H)

• Loss: 0-5 vs Ipswich Town (A)

• Loss: 0-1 vs Middlesbrough (A)

• Loss: 0-1 vs Millwall (H)

Southampton have struggled to secure victories, drawing three of their last five games and losing the other two. Their inability to convert draws into wins, as seen in their 1-1 draw against Middlesbrough at home, suggests a lack of clinical finishing. This could impact their performance against Sheffield United, where they will need to be more decisive in front of goal to overcome their opponents.

• Draw: 1-1 vs Middlesbrough (H)

• Loss: 1-3 vs Hull City (A)

• Draw: 0-0 vs Portsmouth (H)

• Draw: 2-2 vs Watford (A)

• Loss: 1-2 vs Stoke City (H)

The head-to-head record between Sheffield United and Southampton shows a competitive history, with Sheffield United winning two of the last five encounters and Southampton winning two, with one draw. The most recent match in 2009 saw Sheffield United triumph 2-1 away at Southampton, indicating they have the capability to secure a positive result in this fixture.

• Southampton 1-2 Sheffield United (03 Feb 2009)

• Sheffield United 0-0 Southampton (21 Oct 2008)

• Southampton 3-2 Sheffield United (04 May 2008)

• Sheffield United 1-2 Southampton (29 Sep 2007)

• Sheffield United 3-0 Southampton (25 Mar 2006)

• Jamie Shackleton (Foot) - Doubt

• Tom Davies (Muscle) - Doubt

• Ollie Arblaster (Leg) - Doubt

• Welington (Ankle) - Doubt

• Samuel Edozie (Knock) - Doubt

• Predicted lineup: Cooper, Tanganga, McGuinness, Mee, Burrows, Hamer, Peck, Ogbene, O’Hare, Soumaré, Campbell

Sheffield United's predicted lineup suggests a focus on defensive solidity with players like Tanganga and Mee, while relying on the attacking threat of Campbell and O’Hare to exploit any Southampton weaknesses.

• Predicted lineup: McCarthy, Edwards, Wood, Quarshie, Manning, Jander, Charles, Fellows, Azaz, Armstrong, Stewart

Southampton's predicted lineup indicates a need for creativity and goal-scoring prowess from players like Armstrong and Azaz, while maintaining a solid defensive structure with Edwards and Wood.

• Sydie Peck vs Caspar Jander: This midfield duel will involve a close contest with Sheffield United's Peck trying to outmaneuvre Southampton's Jander.

• Ben Mee vs Ross Stewart: Sheffield United's central defender Mee will need to protect against Southampton's energetic striker Stewart.

• Tyrese Campbell (Sheffield United): Tyrese Campbell's pace and finishing ability make him a crucial player for Sheffield United's attack.

• Shea Charles (Southampton): Shea Charles's versatility and composure in midfield are vital for Southampton's performance.

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Odds and market details are accurate as of the time of publication.