Chelsea vs Ajax: Predictions, Betting odds, Lineups, Preview

Explore Coral's detailed preview for Chelsea vs Ajax in the Champions League. Stats, odds, predictions, and lineups for the 20:00 BST match.

• Fixture: Chelsea vs Ajax

• Date: Wednesday, 22 October 2025

• Kick-off: 20:00 BST

• Venue: Stamford Bridge

Chelsea's recent form suggests they could dominate possession and create scoring opportunities against Ajax. Their victory against Benfica at home indicates a strong defensive setup and an ability to capitalise on counter-attacks, which could be crucial against Ajax's struggling defence. However, their loss to Bayern Munich away shows vulnerability when facing high-pressing teams, which Ajax might attempt to exploit. If Chelsea can maintain their defensive solidity and exploit Ajax's weaknesses, they should have the upper hand.

Ajax, on the other hand, have been struggling, losing both of their recent matches convincingly. Their defeats to Marseille and Inter highlight a lack of defensive organisation and difficulty in scoring goals. Against Chelsea, Ajax will need to be more disciplined at the back and more clinical in front of goal. However, given their current form, it seems unlikely they will be able to turn the tide against a more confident Chelsea side.

Chelsea's recent results show a mixed bag of performances. Their win against Benfica at home demonstrates their capability to secure victories against strong opponents, suggesting a solid foundation for this match. However, the loss to Bayern Munich away indicates areas for improvement, particularly in dealing with high-pressing teams. This experience could be beneficial as they prepare to face Ajax, potentially allowing them to adjust their tactics to maintain control and exploit Ajax's defensive frailties.

Recent Champions League results:

• Win: 1-0 vs Benfica (H)
• Loss: 1-3 vs FC Bayern München (A)

Ajax's recent form has been poor, with heavy losses to Marseille and Inter. These results indicate significant issues in both defence and attack, which could be a concern against a more in-form Chelsea side. Ajax will need to drastically improve their defensive organisation and find a way to be more effective in front of goal if they are to have any chance of competing. Their current form suggests they may struggle to keep Chelsea at bay.

Recent Champions League results:

• Loss: 0-4 vs Olympique Marseille (A)

• Loss: 0-2 vs Inter (H)

The head-to-head record between Chelsea and Ajax shows a closely contested rivalry, with a narrow win for Chelsea and a 4-4 in their last two encounters. The most recent match saw Chelsea securing a 1-0 victory away in Amsterdam. This history suggests that while the matches can be competitive, Chelsea have had the upper hand overall.

Recent Champions League results:

• Chelsea 4-4 Ajax (05 Nov 2019)

• Ajax 0-1 Chelsea (23 Oct 2019)

• Dario Essugo (Thigh) - Out

• Liam Delap (Hamstring) - Out

• Levi Colwill (Knee) - Out

• Mykhailo Mudryk (Suspended) - Out

• Cole Palmer (Groin) - Doubt

• João Pedro (Suspended) - Out

• Enzo Fernandez (Knee) - Doubt

• Reece James (Leg) - Doubt

• Tosin Adarabioyo (Calf) - Doubt

• Wesley Fofana (Head) - Doubt

• Kasper Dolberg (Stomach) - Doubt

• Branco van den Boomen (Back) - Doubt

• Owen Wijndal (Unknown) - Doubt

• Youro Reeger (Unknown) - Doubt

Predicted lineup: Sánchez (GK), James (DF), Acheampong (DF), Chalobah (DF), Cucurella (DF), Caicedo (MF), Fernández (if fit) (MF), Neto (MF), Santos (MF), Garnacho (MF), Guiu (AT)

Chelsea's predicted lineup suggests a focus on maintaining possession and exploiting the wings, with Neto and Garnacho likely to provide width and creativity. The inclusion of Guiu up front indicates an intent to capitalise on any defensive lapses from Ajax.

Predicted lineup: Jaros (GK), Gaaei (DF), Sutalo (DF), Baas (DF), Rosa (DF), Mokio (MF), Taylor (MF), Edvardsen (MF), Gloukh (AT), Godts (AT), Weghorst (AT)

Ajax's predicted lineup points to a strategy of counter-attacking, with Taylor and Mokio in midfield tasked with breaking up play and launching quick transitions. The attacking trio of Gloukh, Godts, and Weghorst will need to be sharp to exploit any opportunities against Chelsea's defence.

• Marc Guiu vs Youri Baas: This duel will see Chelsea's forward Guiu looking to outpace and outmanoeuvre Ajax's defender Baas.

• Moises Caicedo vs Jorthy Mokio: Chelsea's midfielder Caicedo will aim to control the midfield and disrupt Ajax's playmaker Mokio.

• Pedro Neto (Chelsea): Neto's creativity and ability to unlock defences make him a crucial player for Chelsea in this match.

• Kenneth Taylor (Ajax): Taylor's role in breaking up play and initiating counter-attacks will be vital for Ajax's chances.

Fans in the UK are able to watch Chelsea vs Ajax on TNT Sports 2 and TNT Sports Ultimate at 20:00 BST on Wednesday, 22 October 2025

Coral is predicting that the score will be Chelsea 2-0 Ajax in the match between Chelsea vs Ajax

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